Aminopeptidase N expression in the endometrium could affect endometrial receptivity
نویسندگان
چکیده
منابع مشابه
Human Endometrial Receptivity and Embryo- Endometrium Interactions
Infertility is an increasing medical and social problem affecting more than 10% of couples worldwide. Many underlying causes of human infertility have been overcome by assisted reproductive techniques; nevertheless, the implantation process remains one of the rate-limiting step as regards the success of the treatment. A prerequisite for successful implantation is the adequate preparation of a r...
متن کاملGnRH antagonists may affect endometrial receptivity.
OBJECTIVE HOXA10 is an essential regulator of endometrial receptivity. To determine the effect of GnRH antagonists on endometrial receptivity, we assessed endometrial HOXA10 expression in GnRH antagonist, GnRH agonist, and natural cycles. DESIGN Prospective case-control study. SETTING University academic medical center. PATIENT(S) Nineteen subjects were included: 12 subjects underwent con...
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While in-vitro fertilization (IVF) was initially developed in women with tubal factor infertility, recent clinical studies have suggested that the presence of hydrosalpinges lowers implantation and pregnancy rates. We postulated that these hydrosalpinges cause impaired endometrial receptivity. A total of 103 women with hydrosalpinges were prospectively evaluated, and compared with 55 infertile ...
متن کاملIon channels in the endometrium: regulation of endometrial receptivity and embryo implantation.
BACKGROUND Although embryo implantation is a prerequisite for human reproduction, it remains a poorly understood process. The molecular mechanisms regulating endometrial receptivity and/or embryo implantation are still largely unclear. METHODS Pubmed and Medline literature databases were searched for articles in English published up to December 2013 with relevant keywords including 'endometri...
متن کاملGene expression profile of the human endometrial receptivity: comparison
26 27 Background: The adjunction of exogenous hormones for controlled ovarian stimulation 28 (COS) may alter endometrial receptiveness. In order to identify the genes mis-regulated under 29 COS, we compared the endometrium gene expression profiles, from the same patients, in a 30 natural cycle and in a subsequent COS cycle. Methods: For the same normal-responder 31 patients (n=21), endometrial ...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2019
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2019.04.174